Our commitment to our clients is to stay on the cutting edge of technology providing the fastest, most accurate results possible. Each of our systems is interfaced to computers running Analyst™

Equipment

• (8) Sciex API 5000 triple quadrupole LC/MS/MS
• (11) Sciex API 4000 triple quadrupole LC/MS/MS
• (1) Thermo LXQ 2-D ion trap LC/MS/MS
• (10) Shimadzu Nexera UPLC systems with low carryover SIL-30AC autosamplers
• (5) Waters Acquity UPLC systems
• (4) Tomtec Quadra 4 liquid handling systems
• (2) Hamilton STAR liquid handling systems
• (2) Hamilton STARlet liquid handling systems
• (1) PE Multiprobe IIEX liquid handling system (method optimization)

Technology

Our bioanalytical capabilities are supported by Thermo Electron Watson™ LIMS, a highly specialized software system designed to provide compliance with GLP and 21 CFR Part 11 regulations. Beginning with flexible study input, Bioanalytical Sciences uses Watson™ for sample management, analytical run planning, instrument interfacing, assay performance evaluation, data analysis and data reporting. Additionally, automated data transfer from Watson™ to Pharsight WinNonlin™ maintains Part 11 compliance for pharmacokinetic analysis and expedites the completion of PK/TK reports. Other export capabilities are also available to provide data in various formats.

Study reports are produced for easy incorporation into electronic submissions. Liquent InSight Publisher™ applies PDF rendering technology to automatically compile source documents with varying file formats into one seamless publication. Additionally, our Bioanalytical Sciences utilizes NuGenesis™ software for electronic capture of representative chromatography to meet industry guidelines. These technologies support Part 11 compliant data reporting from Watson™ and other software programs.

Robotics

Worldwide Clinical Trials Bioanalytical Sciences has expanded its automated sample and liquid handling capabilities adding Hamilton STAR, STARlet, Tomtec Quadra 4 SPE units, Perkin Elmer Multiprobe and Gyrolab xP™ Workstation instruments. These robotic workstations offer state-of-the-art parallel processing with the latest feedback technology to ensure a high degree of accuracy and precision. Bioanalytical Sciences has also automated a variety of method development activities, utilizing the flexibility of the PE MultiProbe liquid handler and applied the latest extraction and separation technology to provide high quality assays.Methods are optimized and undergo extensive assessment prior to validation.