CSF biomarker variability in the Alzheimer’s Association quality control program

May 2013 -

Niklas Mattsson, Ulf Andreasson, Staffan Persson, Maria C. Carrillo, Steven Collins, Sonia Chalbot, Neal Cutler, Diane Dufour-Rainfray, Anne M. Fagan, Niels H. H. Heegaard, Ging-Yuek Robin Hsiung, Bradley Hyman, Khalid Iqbal, et al.

The Development of a Data Dictionary and Syntax for Optimizing the Utilization of the Coalition Against Major Diseases (CAMD) Alzheimer’s Disease Clinical Trial Database

Jul 2012 -

Lisle R. Kingery, Ph.D., Beth Friedmann, Psy.D., Erin Kornsey, M.A., Neal R, Cutler, M.D. & Henry J. Riordan, Ph.D. - Presented at the Alzheimer’s Association International Conference, 2012 (PDF)

Reliability and Reliable Change of the CAARS Self-Report Short Version and Observer Screening Version Scales in an Adult ADHD Clinical Trial

Jun 2012 -

Lisle Kingery, Ph.D., Beth Friedmann, Psy.D., Erin B. Kornsey, M.S., Cordelia Zakrajsek, M.Ph., Neal R. Cutler, M.D., Henry J. Riordan, Ph.D. – Presented at NCDEU 2012: An American Society of Clinical Psychopharmacology meeting (PDF)

CSF Sample Acquisition and Analyses for Translational Research Purposes

May 2012 -

Henry J. Riordan, Ph.D., Michael F. Murphy, M.D., Ph.D., William Nowatzke, Ph.D., Mark Leibowitz, M.D. & Neal R. Cutler, M.D. - Abstract presented at the 12th International Springfield / Stockholm Symposium on Advances in Alzheimer’s Therapy 2012 (PDF)

Quantitative Analysis of Cognitive and Imaging Biomarkers in Schizophrenia Medication Trials

Apr 2012 -

Henry J. Riordan, Ph.D., Paul J. Moberg, Ph.D., Kathy Dawson, Ph.D., Neal R. Cutler, M.D. - Presented at Cognition in Schizophrenia 2012: A Satellite Meeting of the Schizophrenia International Research Society (PDF)

A Randomized Crossover Study of the Sleep Effects of Naltrexone in Healthy Normal Subjects

Apr 2012 -

Mark Leibowitz M.D., James M. Andry M.D., Henry J. Riordan Ph.D., John Sramek Pharm.D. & Neal R. Cutler M.D - Presented at the Society of Biological Psychiatry, 2012 Annual Meeting (PDF)

Meta-Analysis of Structural Magnetic Resonance Imaging (sMRI) Biomarkers In Schizophrenia Medication Trials

Feb 2012 -

Henry J. Riordan, Ph.D., Kathy Dawson, Ph.D., Neal R. Cutler, M.D., Chwen-Cheng Nathan Chen, M.D., Ph.D., Steven Potkin, M.D. & Susan DeSanti, Ph.D. - Presented at the International Society for CNS Clinical Trials and Methodology meeting (PDF)

The Death of CNS Drug Development: Overstatement or Omen?

Dec 2011 -

Neal R. Cutler M.D., Henry J. Riordan Ph.D. - Journal for Clinical Studies Vol 3 (6) pp 12-15 (PDF)

Updated Diagnostic Criteria for Alzheimer’s Disease: Implications for Clinical Trials

Sep 2011 -

Henry J. Riordan, Ph.D., Erin B. Kornsey, M.S. - Journal for Clinical Studies Vol 3 (5) pp 12-15 (PDF)

Evaluation of Beta Amyloid Loss to CSF Sample Collection and Storage Containers

Jul 2011 -

Henry J. Riordan, Ph.D., Yoka Thomas, Neal R. Cutler,M.D., Mark Leibowitz, M.D., Kathryn Rogers, Kathryn Dawson, Ph.D., Michele Malone, Steve Unger, Ph.D., William Nowatzke, Ph.D. Presented at the Alzheimer’s Association International Conference (PDF)

FDA’s New Risk Evaluation and Mitigation Strategy for Opioids

Jul 2011 -

Henry J Riordan, Ph.D. - Journal for Clinical Studies, Vol 3 (4) pp 14-15 (PDF)

"Racial Disparities in a Community Based Sample of a Novel Memory Screening Protocol"

Jun 2011 -

Erin B. Kornsey, M.S., Barry W. Rovner, M.D., Robin J. Casten, Ph.D. (PDF)

Racial Differences in the Recognition of Cognitive Dysfunction in Older Persons Support

Jun 2011 -

Erin B. Kornsey, M.S., Barry W. Rovner, M.D., Robin J. Casten, Ph.D. (PDF)

Complying with FDA Guidance on the Prospective Assessment of Sucidiality in Clinical Trials

May 2011 -

Henry J Riordan, Ph.D. - Journal for Clinical Studies, Vol 3 (3) pp10-11 (PDF)

Optimizing the Assessment of CNS Side Effects of a Novel Neuropathic Pain Compound

Apr 2011 -

Henry J. Riordan, Ph.D., Andrew Kuhlman, M.S., Kathryn Dawson, Ph.D., Erin Kornsey, M.S., Alex Miller, Bethanne Friedmann, Psy.D., Neal R. Cutler, M.D. - Presented at the Society for Biological Psychiatry, Annual Meeting (PDF)

Vaptans: A Potential New Approach for Treating Chronic Hyponatremia in Psychotic Patients

Apr 2011 -

Richard C. Josiassen, Ph.D., Jessica L. Curtis, Rita A. Shaughnessy, M.D., Dawn M. Filmyer, B.S., Brett Audino, Nina Skuban, M.D. - Presented at the International Congress on Schizophrenia Research (PDF)

The Role of Amyloid Biomarkers in Accelerating Alzheimer’s Disease Drug Development.

Mar 2011 -

Henry J, Riordan, Ph.D. - Journal for Clinical Studies, Vol 3 (2) pp 10-11 (PDF)

The Impact of Site Characteristics on Efficacy Measures

Feb 2011 -

Bethanne Friedmann, Psy.D. , Erin B. Kornsey, M.S., Kathryn Dawson, Ph.D., Henry J. Riordan, Ph.D., Michael F. Murphy, M.D., Ph.D., Neal R. Cutler, M.D. - Presented at the International Society for CNS Clinical Trials and Methodology meeting (PDF)

FDA’s New Guidance on Biomarker and Patient Reported Outcome Qualification

Jan 2011 -

Henry J. Riordan, Ph.D. - Journal for Clinical Studies, Vol 3 (1), pp 12-13 (PDF)

The Impact of DSM-5 on Psychiatric Clinical Trials: Challenges and Opportunities.

Nov 2010 -

Henry J. Riordan, Ph.D. - Journal for Clinical Studies, pp 14-15 (PDF)

Innovative Designs for Chronic Pain Trials

Sep 2010 -

Henry J Riordan, Ph.D., Michael F. Murphy, M.D., Ph.D. - Journal for Clinical Studies, pp 30-35 (PDF)

The Impact of Site Rater Monitoring and Refresher Training on Enrollment in a MCI Phenotype Trial

Aug 2010 -

Bethanne Friedmann, Psy.D., Erin B. Kornsey, M.S., Michael F. Murphy, M.D., Ph.D., Neal R. Cutler, M.D. - Presented at the European College of Neuropsychopharmacology (ECNP) Annual Meeting (PDF)

Validity of semantic memory test as predictor of change in ADAS-cog scores in MCI

Aug 2010 -

Erin B. Kornsey, M.S., Bethanne Friedmann, Psy.D., Michael F. Murphy, M.D., Ph.D., Neal R. Cutler, M.D. - Presented at the European College of Neuropsychopharmacology (ECNP) Annual Meeting (PDF)

Site vs remote inter-rater reliability of the PANSS and Information Demand

Jun 2010 -

Bethanne Friedmann, Psy.D., Henry Riordan, Ph.D., Erin Kornsey, M.S., Evan Braxton, Michael F. Murphy, M.D., Ph.D., Neal R. Cutler, M.D. - Presented at NCDEU 2010: An American Society of Clinical Psychopharmacology meeting (PDF)

Systematically Elicited Neuropsychiatric Adverse Events and Various Rating Scale Assessments of Withdrawal Symptoms in Smoking Cessation Trials

Jun 2010 -

Henry Riordan, Ph.D., Dahlia Garza, M.D., Anjan Chatterjee, M.D., M.Ph., Li-Jung Tseng, Ph.D., Michael F Murphy, M.D. Ph.D. - Presented at NCDEU 2010: An American Society of Clinical Psychopharmacology meeting (PDF)

Critical Pathways to Success in CNS Drug Development

Mar 2010 -

Neal R. Cutler, M.D., John J. Sramek, Pharm.D., Michael F. Murphy, M.D., Ph.D, Henry J Riordan, Ph.D., Peter Biek, M.D., Ph.D., Angelico Carta, M.D. (Publisher: Wiley Blackwell)

A post-hoc Examination of patient characteristics: Implications for enhanced medical surveillance

Jan 2010 -

Bethanne Friedmann, PsyD1, Henry J. Riordan, Ph.D.1, Erin B. Kornsey, MS1, Kenneth Williams, MD1, Kevin Cox, MD2, Neal R. Cutler, MD2,Michael F. Murphy, MD, PhD1

A Meta-Analysis of Computerized Assessment Batteries in Alzheimer’s Disease Treatment Trials

Dec 2009 -

Henry J. Riordan, Neal R. Cutler, Farzin Irani, Paul J. Moberg. The International Society for CNS Clinical Trials and Methodology (ISCTM) 2010.

A Comparison of Rating Quality between Subtitle and Spoken Hamilton Depression Rating Scale Interviews

Dec 2008 -

Bethanne Friedmann, PsyD, Henry Riordan, Ph.D., Evan Braxton, Christopher J. Weber, Ph.D., Michael F. Murphy, M.D., Ph.D., Neal R. Cutler, M.D. European College of Neuropsychopharmacology (ECNP) 2009.

A Meta-Analysis of Computerized Assessment Batteries in Schizophrenia Medication Trials

Dec 2008 -

Henry Riordan, Luke Eastman, Lauren Hoffman, Neal Cutler, Paul J. Moberg. The International Society for CNS Clinical Trials and Methodology (ISCTM) 2009.

Determination of ?-Amyloid (1-42) Concentrations in Healthy Volunteers during Continuous CSF Sampling

Dec 2008 -

Nowatzke, W., Leibowitz, M., Breau, A., Delhaye, R., Bjornstal, O., Wells, E., Rogers, K., Zhang, W., Henry Riordan. 2009.

Does Naltrexone Block Appearance of Initial Morphine Side Effects in Healthy Volunteers?

Dec 2008 -

John J. Sramek, Pharm. D., Sherilyn A. Adcock, Ph.D. R.Ph., Neal R. Cutler, M.D. 2008.

Rapid Development of Tolerance to Adverse Events after Oral Morphine Administration to Opiate Naïve Subjects

Dec 2008 -

John J. Sramek, Pharm,D., Sherilyn Adcock, Ph.D., Henry Riordan, Ph.D., Neal R. Cutler, M.D. 2009

The Effect of Simultaneous Translations and Experience on Positive and Negative Syndrome Scale (PANSS) Scoring Performance for Eastern European Raters

Dec 2008 -

Bethanne Friedmann, Psy.D., Henry Riordan, Ph.D, Evan Braxton, Christopher J. Weber, Ph.D., Michael F. Murphy, M.D., Neal R Cutler, M.D. New Clinical Drug Evaluation Unit (NCDEU) 2009.

Use of Naltrexone to Block Opioid Side Effects in Healthy Volunteers: Effects of Dose and Food

Dec 2008 -

Henry Riordan, Ph.D., Barbara Newberry, John Sramek, Pharm. D., Sherilyn Adcock, Ph.D. R.Ph., Neal R. Cutler, M.D. American Pain Society (APS) 2009.

Alzheimer's Disease; Optimizing the Development of the Next Generation of Therapeutic Compounds

Jun 2008 -

Michael F. Murphy, M.D., Ph.D.; John J. Sramek, Pharm.D.; Neil M. Kurtz, M.D.; Angelico Carta, M.D.; Neal R. Cutler, M.D.

Optimizing Therapeutic Development in Diabetes

Dec 1998 -

G. Alexander Fleming , Stanford S. Jhee , Robert F. Coniff , Henry J. Riordan , Michael F. Murphy , Neil M. Kurtz , Neal R. Cutler

Accelerating CNS Drug Development

Dec 1997 -

Neal R. Cutler , John J. Sramek , Neil M. Kurtz , Michael F. Murphy , Angelico Carta

Accelerating CNS Drug Development

Dec 1997 -

Neal R. Cutler , John J. Sramek , Neil M. Kurtz , Michael F. Murphy , Angelico Carta

Optimizing the Development of Antipsychotic Drugs

Jun 1997 -

John J. Sramek, Pharm.D; Neal R. Cutler, M.D.; Neil M. Kurtz, M.D.; Michael F. Murphy, M.D., Ph.D.; Angelico Carta, M.D.

Understanding Alzheimer’s Disease (Understanding health & sickness)

Feb 1997 -

Neal R. Cutler, M.D.; John J. Sramek, Pharm.D

Anxiolytic Compounds: Perspectives in Drug Development

Jan 1996 -

Neal R. Cutler, M.D.; John J. Sramek, Pharm.D; Neil M. Kurtz, M.D.

Alzheimer's Disease: Clinical and Treatment Perspectives

Oct 1994 -

Neal R. Cutler, M.D.; C. G. Gottfries, M.D.; K. Siegfried M.D.

Alzheimer's Disease: Optimizing Drug Development Strategies

Jun 1994 -

Neal R. Cutler, M.D.; John J. Sramek, Pharm.D.; Amy E. Veroff, Ph.D. (20 July 1994)

Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology

Jun 1994 -

Neal R. Cutler M.D., John J. Sramek Pharm.D., Prem K. Narang Ph.D.